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eBook Advances in the Immunopathogenesis of Multiple Sclerosis ePub

eBook Advances in the Immunopathogenesis of Multiple Sclerosis ePub

by Domencio Gambi,Allesandra Lugaresi,Paolo A. Muraro

  • ISBN: 884700067X
  • Category: Medicine
  • Subcategory: Medicine
  • Author: Domencio Gambi,Allesandra Lugaresi,Paolo A. Muraro
  • Language: English
  • Publisher: Springer; 1999 edition (August 13, 1999)
  • Pages: 90
  • ePub book: 1780 kb
  • Fb2 book: 1722 kb
  • Other: lrf lrf docx doc
  • Rating: 4.2
  • Votes: 685

Description

MURARO, A. LUGARESI, D. GAMBI Many of the pathological aspects of multiple sclerosis (MS) lesions have been known for over a century

price for USA in USD (gross). MURARO, A. GAMBI Many of the pathological aspects of multiple sclerosis (MS) lesions have been known for over a century.

Domencio Gambi, Allesandra Lugaresi, Paolo A. Muraro.

A central role in the possible mechanisms leading to myelin destruc­ tion has been attributed to T lymphocytes reactive to myelin antigens

MURARO, A. A central role in the possible mechanisms leading to myelin destruc­ tion has been attributed to T lymphocytes reactive to myelin antigens. Studies on the myelin antigen-specific T cell repertoire have contributed significant advances to our knowledge of autoimmunity (Chapters 1,2).

Multiple sclerosis (MS) has been considered for a long time a typical inflammatory demyelinating disease of the central nervous system due to autoimmunity targeting oligodendrocytes with sparing of axons until advanced stages of the disease. For this reason, most of the earliest experimental studies focused on the role of cytokines and chemokines at the site of oligodendrocytes loss and on the.

However, current studies indicate that multiple sclerosis is largely a heterogeneous disease process, which .

However, current studies indicate that multiple sclerosis is largely a heterogeneous disease process, which involves both innate and adaptive immune-mediated inflammatory mechanisms that ultimately contribute to demyelination and neurodegeneration. A better understanding of immune-mediated mechanisms in the pathogenesis of multiple sclerosis and the contribution of environmental risk factors toward the development of multiple sclerosis will help further improve therapeutic approaches to prevent disease progression.

MURARO, A.

Books related to Advances in the Immunopathogenesis of Multiple Sclerosis. Books related to Advances in the Immunopathogenesis of Multiple Sclerosis.

Personal Name: Gambi, D. (Domenico), 1936 .

Advances in the Immunopathogenesis of Multiple Sclerosis. 2 - The naive and memory MBP-reactive CD4+ T cell repertoire: implications for the autoimmune concept in multiple sclerosis. Daniel Gambí, Paolo A Muraro, Alessandra Lugaresi, U. Ecari. 1 - The affinity spectrum of myelin basic protein-reactive T cells.

Электронная книга "Experimental Models of Multiple Sclerosis", Ehud Lavi, Cris S. Constantinescu

Электронная книга "Experimental Models of Multiple Sclerosis", Ehud Lavi, Cris S. Constantinescu. Эту книгу можно прочитать в Google Play Книгах на компьютере, а также на устройствах Android и iOS. Выделяйте текст, добавляйте закладки и делайте заметки, скачав книгу "Experimental Models of Multiple Sclerosis" для чтения в офлайн-режиме.

P.A. MURARO, A. LUGARESI, D. GAMBI Many of the pathological aspects of multiple sclerosis (MS) lesions have been known for over a century. It is only recently, however, that different patterns of demyelination have been linked to distinct pathways of immune-mediated tissue destruction. In particular, the inter-individual heterogeneity of MS lesions has suggested that different mechanisms may act in different patients, accounting for the variability observed in clinical course, immunological findings in peripheral blood and cere­ brospinal fluid (CSF), and response to immunomodulatory treatments. To provide an overview of the basic mechanisms possibly involved in MS lesion initiation and development, an international meeting was organized in the context of the annual Congress of the Italian Neuroimmunology Association (AINI), held at the University of Chieti, in Chieti Italy on 29 October 1998. The high standard of presentations prompted us to report them in extended form, to highlight recent pro­ gress in the understanding of basic mechanisms sustaining MS immuno­ pathogenesis. A central role in the possible mechanisms leading to myelin destruc­ tion has been attributed to T lymphocytes reactive to myelin antigens. Studies on the myelin antigen-specific T cell repertoire have contributed significant advances to our knowledge of autoimmunity (Chapters 1,2).