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eBook A Primer of Genome Science ePub

eBook A Primer of Genome Science ePub

by Spencer V. Muse,Spencer Muse,Greg Gibson

  • ISBN: 0878932348
  • Category: Medicine and Health Sciences
  • Subcategory: Other
  • Author: Spencer V. Muse,Spencer Muse,Greg Gibson
  • Language: English
  • Publisher: Sinauer Associates; 1st edition (December 3, 2001)
  • Pages: 347
  • ePub book: 1810 kb
  • Fb2 book: 1211 kb
  • Other: lrf rtf azw mobi
  • Rating: 4.3
  • Votes: 714

Description

He earned a Bachelor's Degree in Statistics and a P.

He earned a Bachelor's Degree in Statistics and a P. in Statistics and Genetics, both at NCSU (the latter with Bruce Weir and Trudy Mackay). Dr. Muse was the recipient of a Sloan Foundation Young Investigator Award (1997-2001).

Greg Gibson (Author), Spencer V. Muse (Author). A Primer of Genome Science bridges the gap between standard genetics textbooks and highly specialized, technical, and advanced treatments of the subdisciplines

Greg Gibson (Author), Spencer V. ISBN-13: 978-0878932320. A Primer of Genome Science bridges the gap between standard genetics textbooks and highly specialized, technical, and advanced treatments of the subdisciplines. It provides an affordable and up-to-date introduction to the field that is suited to advanced undergraduate or early graduate courses. Bioinformatic principles and experimental strategies are explained side-by-side with the experimental methods, establishing a framework that allows teachers to explore topics and the literature at their own pace.

primer of genome science. Sinauer Associates, 2009. DA Kirby, SV Muse, W Stephan. Proceedings of the National Academy of Sciences 92 (20), 9047-9051, 1995. Testing for equality of evolutionary rates. Genetics 132 (1), 269-276, 1992. PowerMarker: new genetic data analysis software.

Genome science has matured as a discipline to the point where it is now incorporated as a regular part of the genetics curriculum in universities

Genome science has matured as a discipline to the point where it is now incorporated as a regular part of the genetics curriculum in universities. It provides an affordable introduction to the field that is suited to advanced undergraduate or early graduate courses.

A Primer of Genome Science bridges the gap between standard genetics textbooks and highly specialized, technical, and advanced treatments of the subdisciplines.

A Primer of Genome Science. Greg Gibson and Spencer V. Muse. Publication Date - January 2009. Instructor's Resource Library.

Discover new books on Goodreads. See if your friends have read any of Spencer V. Muse's books. Spencer V. Muse’s Followers. None yet. Muse’s books. A Primer of Genome Science by. Greg Gibson, Spencer V. Gibson, Greg; Muse, Spencer . 1966-.

This book focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications.

A Primer of Genome Science Greg Gibson; Spencer Muse Palgrave 9780878932320 : A Primer of Genome Science bridges the gap between standard genetics textbooks and highly specialized, t. This book focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. It also features topics organized around biological problems. Seidel . Weiss B. Название: Bioinformatics and Genome Analysis ISBN: 3540428933 ISBN-13(EAN): 9783540428930 Издательство: Springer Рейтинг

Genome science as a discipline is less than five years old, but has already spawned a revolution in the way in which genetics is taught in universities, approached by academic researchers, and applied by pharmaceutical and agricultural research companies. While over a dozen new journals devoted to genomics have appeared in the last few years, no introductory textbook that covers the range of disciplines incorporated into genome science has materialized, until now. A Primer of Genome Science bridges the gap between standard genetics textbooks and highly specialized, technical, and advanced treatments of the subdisciplines. It provides an affordable and up-to-date introduction to the field that is suited to advanced undergraduate or early graduate courses. Bioinformatic principles and experimental strategies are explained side-by-side with the experimental methods, establishing a framework that allows teachers to explore topics and the literature at their own pace.

The Primer is organized into six chapters. Each chapter includes: exercises that can be worked by students using the internet and freely available software for analysis of genomic data; discussion questions; a summary; and suggestions for further reading. An Appendix includes a glossary of terms, with a brief review of key genetic concepts.

Comments

Danial Danial
This somewhat understated book may be overlooked based on its title, and yet it represents the best book currently in print to provide a solid overview of the science and issues in genome science, functional and structural genomics, and the subdiscipline proteomics. Chapter 1 describes current progress with mapping genomes, including the human genome and other genomes in plants and animals. Chapter 2 describes sequencing approaches and gene identification. Chapter 3 deals with gene expression and technologies. Chapter 4 focuses on proteomics including brief introductions to 2D-PAGE and mass spectrometry. This chapter also briefly introduces the reader to structural genomics, or the prediction of protein structure based on sequence through threading and modeling. After a chapter on single nucletide polymorphisms and genotyping the book concludes with a chapter on integrating genome studies including the use of in silico approaches.
Although scant in detail in parts, a major strength of the book is the wide coverage given to science of genomics and its offshoots. Overall an excellent course text for undergraduate or early postgraduate students or others interested in these emerging disciplines. I am not aware of any competing texts which such coverage and certainly not at the price of this one.
Vit Vit
With the basic science being so new and changing so rapidly, this second edition is timely and welcome. Virtually every chapter has been re-written to bring it up to date. The result is a text suitable for use in upper under grad or beginning grad level course in functional genomics or bioinformatics. The six chapter headings are:

Genome Projects: Organization and Objectives

Genome Sequencing and Annotation

SNPs and Variation

Gene Expression and the Transcriptome

Proteomics and Functional Genomics

Integrative Genomics.

The book is well written and profusely illustrated with color drawings and photographs. The book is closely allied with the web in form of accessable databases and the like which may keep it from going out of date so fast.

With most text books being so expensive, this book is a definite sleeper in the field.
Danrad Danrad
The book is very poorly written and is too difficult to follow to be called a "primer." Authors often focus on actual software tools and how to use them rather than the science behind them.
To be fair, the graphics offered in the book are excellent and sometimes are the only way to understand a difficult concept.
The preface says to be familiar with "the content of a typical 300 level undergraduate course in genetics" -- it should be a definite prerequisite for reading this book.
Malanim Malanim
Except the computer-aided drug design, this book covers all the basic theory and useful information of bioinformatics. I recommended this book for anyone who needs to use the bioinformatics web, software tools. For the clinical physician, medical student, and molecular biology scientist, this book is very useful. Especially when you have no time to understanding the detail mathematic calculation, it quickly gives you a whole view and introduction.
Malodor Malodor
Every technician and/or PI should own a copy of this text for their lab. With the logical diagrams and full explanation of the text, this book is really condensed and assumes some knowledge of molecular biology. This book does not assume knowledge of genomics, but rather serves as a manual.