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eBook Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology) ePub

eBook Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology) ePub

by David M. Terrian

  • ISBN: 1588290751
  • Category: Medicine and Health Sciences
  • Subcategory: Other
  • Author: David M. Terrian
  • Language: English
  • Publisher: Humana Press; 2003 edition (December 9, 2002)
  • Pages: 333
  • ePub book: 1362 kb
  • Fb2 book: 1767 kb
  • Other: rtf lrf mbr doc
  • Rating: 4.3
  • Votes: 610

Description

Methods and Protocols.

Methods and Protocols.

Cancer Cell Signaling: Methods and Protocols (Methods in Molecular Biology Vol 218). Download (pdf, . 0 Mb) Donate Read. Epub FB2 mobi txt RTF. Converted file can differ from the original. If possible, download the file in its original format.

Автор: Terrian David M. Название: Cancer Cell Signaling, Methods and Protocols Издательство . This book covers various findings relevant to cellular and molecular functions of polyamines.

This book covers various findings relevant to cellular and molecular functions of polyamines. It also provides the underlying conceptual basis and knowledge regarding potential therapeutic targeting polyamines and polyamine metabolism.

A collection of readily reproducible experimental methods for studying the subversion of normal cell signaling that .

A collection of readily reproducible experimental methods for studying the subversion of normal cell signaling that leads to cancer. Presented in step-by-step detail to ensure successful results, the methods include proven techniques for the investigation of apoptosis and cell death, complementary protocols for manipulating and/or monitoring oncogenic signals in cancer cel A collection of readily reproducible experimental methods for studying the subversion of normal cell signaling that leads to cancer.

Most of the methods discussed in this book have been developed in the past 10–15 years and they cover a wide array of approaches . Aberrations of Notch signaling in humans cause both congenital and acquired defects and cancers.

Most of the methods discussed in this book have been developed in the past 10–15 years and they cover a wide array of approaches related or based on mouse and human cell lines, flies, and mice. The first set of chapters focus on genetic methods in flies and mice, methods to image Notch signaling in live organisms or cells, techniques to monitor Notch activity in cells, and procedures to visualize oscillation associated with Notch signaling in cells and tissues.

Product Details Book Publisher: Humana Press (09 December, 2002) ISBN: 1588290751 Book author: David M. Terrian .

Presented in step-by-step detail to ensure successful results, the methods include proven techniques for the investigation of apoptosis and cell death, complementary protocols for manipulating and/or monitoring oncogenic signals in cancer cells, and techniques for studying protein-protein interactions.

Terrian, David M. Publication date. Cytopathology, Nursing - Oncology & Cancer, Laboratory manuals, Pathology, Carcinogenesis, Cellular Pathology, Medical, Medical, Nursing, Microbiology, Life Sciences - Cytology, Oncology, Medical, Oncology, Regulation, Cancer, Cancer cells, Cellular signal transduction, Genetic aspects, Neoplasms, Signal Transduction. Books for People with Print Disabilities. Internet Archive Books. Uploaded by Tracey Gutierres on May 22, 2012.

Get a full overview of Methods in Cell Biology Book Series. Readers can expect to gain knowledge in the most recent differentiation protocols from experts in their respective areas. Most recent Volume: Human Pluripotent Stem Cell Derived Organoid Models.

The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias toward anyone considering setting up a new cytogenetics service

The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias toward anyone considering setting up a new cytogenetics service.

Cells respond to environmental cues through a complex and dynamic network of signaling pathways that normally maintain a critical balance between cellular proliferation, differentiation, senescence, and death. One current research challenge is to identify those aberrations in signal transd- tion that directly contribute to a loss of this division-limited equilibrium and the progression to malignant transformation. The study of cell-signaling m- ecules in this context is a central component of cancer research. From the knowledge of such targets, investigators have been able to productively advance many insightful hypotheses about how a particular cancer cell may misinterpret, or respond inappropriately to, growth regulatory cues in their environment. Despite these key insights, the rapidly evolving nature of cell signaling research in cancer has necessitated a continuous revision of these theoretical constructs and the updating of methods used in their study. One contemporary example of the evolution of this field is provided by an analysis of the Human Genome Project data, which reveal a previously unsuspected diversity in the multigene families encoding for most signaling pathway int- mediates. In assessing the usefulness of a particular methodological approach, therefore, we will need to keep in mind that there is a premium on those p- tocols that can be easily adapted for the analysis of multiple members within a gene family. Cancer Cell Signaling: Methods and Protocols brings together several such methods in cell signaling research that are scientifically grounded within the cancer biology field.