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eBook Antibody Engineering: Methods and Protocols, Second Edition (Methods in Molecular Biology) ePub

eBook Antibody Engineering: Methods and Protocols, Second Edition (Methods in Molecular Biology) ePub

by Patrick Chames

  • ISBN: 1617799734
  • Category: Medicine and Health Sciences
  • Subcategory: Other
  • Author: Patrick Chames
  • Language: English
  • Publisher: Humana Press; 2nd ed. 2012 edition (August 21, 2012)
  • Pages: 734
  • ePub book: 1387 kb
  • Fb2 book: 1483 kb
  • Other: doc mbr lit lrf
  • Rating: 4.7
  • Votes: 898

Description

Methods in Molecular Biology 1827. In. Molecular biology

Methods in Molecular Biology 1827. Molecular biology.

Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their .

Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Show all. Table of contents (40 chapters)

Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a. .

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Antibody Engineering book .

Antibody Engineering book. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Recombinant Antibodies for Cancer Therapy: Methods an.

Recombinant Antibodies for Cancer Therapy: Methods and. Protocols.

Comprehensive and up-to-date, Antibody Engineering: Methods and Protocols provides both laboratory and clinical investigators with a diverse array of the fundamental techniques upon which new and imaginative drug.

Comprehensive and up-to-date, Antibody Engineering: Methods and Protocols provides both laboratory and clinical investigators with a diverse array of the fundamental techniques upon which new and imaginative drug technologies can be successfully developed.

Methods in Molecular Biology. Preface methods to select antibodies for specific proteins, permitting users to determine

Methods in Molecular Biology. This volume of Methods in Molecular Biology focuses on techniques to. determine the function of a gene. methods to select antibodies for specific proteins, permitting users to determine. where and when proteins are present and active in their systems.

Published in Methods in Molecular Biology 2018

Published in Methods in Molecular Biology 2018. Antibody Engineering. oceedings{yE, title {Antibody Engineering}, author {Damien Nevoltris and Patrick Chames}, booktitle {Methods in Molecular Biology}, year {2018} }. Damien Nevoltris, Patrick Chames. Antibody humanization process converts any nonhuman antibody sequence into humanized antibodies. This can be achieved using different methods of antibody design and engineering.

More than ever, antibodies are being recognized as a major drug modality in a variety of diseases, including cancer, autoimmune diseases, infectious diseases, or even neurodegenerative disorders. Over 30 therapeutic antibodies have been approved and novel molecules are entering clinical trials at an average rate of 50 per year and that is predicted to continue well into the future. Notwithstanding the many achievements already made in the field, there is still a lot of room for improvements for these molecules in terms of activity, and a plethora of approaches have been attempted to optimize these molecules. Antibody Engineering: Methods and Protocols, Second Edition was compiled to give complete and easy access to a variety of antibody engineering techniques, starting from the creation of antibody repertoires and efficient ways to select binders from these repertoires, to their production in various hosts, their detailed characterization using various well established techniques, and to the modification and optimization of these lead molecules in terms of binding activity, specificity, size, shape, and more. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and easily accessible, Antibody Engineering: Methods and Protocols, Second Edition serves as an invaluable resource for both experts and those new to the field, and most of all as a source of inspiration for the creation of the antibodies of tomorrow.